Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066758 | 0.97 | L3MBTL1 (0.72) | L3MBTL1ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL1421600 | 0.93 | ABCG2 (0.67) | L3MBTL1ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL19267888 | 0.91 | L3MBTL1 (0.77) | L3MBTL1ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL30376090 | 0.91 | L3MBTL1 (0.77) | L3MBTL1ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL7603078 | 0.89 | L3MBTL1 (0.65) | L3MBTL1ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL29979584 | 0.88 | L3MBTL1 (0.79) | L3MBTL1ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL30376265 | 0.86 | ABCB1 (0.73) | ABCG2MEN1KMT2AALDH1A1ABCB1 | |
| SCHEMBL21206267 | 0.86 | ABCB1 (0.73) | ABCG2MEN1KMT2AALDH1A1ABCB1 | |
| SCHEMBL8068919 | 0.86 | ABCB1 (0.73) | L3MBTL1ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL7306849 | 0.85 | MAPT (0.74) | L3MBTL1ABCG2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371775-B2 | 7-carboxymethyloxy-3′,4′,5-trimethoxy flavone monohydrate, the preparation method and uses thereof | DONG-A PHARMACEUTICALS CO., LTD (KR) | 2008-05-13 | — | — | US | disclosed |
| US-7371775-B2 | 7-carboxymethyloxy-3′,4′,5-trimethoxy flavone monohydrate, the preparation method and uses thereof | DONG-A PHARMACEUTICALS CO., LTD (KR) | 2008-05-13 | — | — | US | disclosed |
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |