Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 0.82 |
| ▸ | ATM | Q13315 | 1/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | OXTR | P30559 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053396 | 0.93 | SMN1; SMN2 (0.86) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL806438 | 0.91 | SMN1; SMN2 (0.83) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL806760 | 0.86 | SMN1; SMN2 (0.75) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL798388 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL16557464 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2OXTRALDH1A1KMT2AMAPT | |
| SCHEMBL10053467 | 0.82 | KMT2A (0.78) | SMN1; SMN2HPGDATML3MBTL1OXTR | |
| SCHEMBL17340105 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL798403 | 0.81 | OXTR (0.69) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL18963016 | 0.77 | MAPT (0.79) | SMN1; SMN2OXTRAVPR1APOLBKMT2A | |
| SCHEMBL3367904 | 0.76 | OXTR (1.00) | SMN1; SMN2HPGDATML3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212134-B2 | Inhibitors of viral entry into mammalian cells | MICROBIOTIX, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |