SCHEMBL806442

SCHEMBL806442

Cc1ccc(C)c2c1CCC2=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
GLA P06280 1/20 0.45
GAA P10253 1/20 0.45
MAOA P21397 3/20 0.43
MAOB P27338 3/20 0.43
DRD4 P21917 1/20 0.38
BRD4 O60885 7/20 0.38
AKT1 P31749 1/20 0.37
AKT2 P31751 1/20 0.37
AKT3 Q9Y243 1/20 0.37
TYMS P04818 2/20 0.35
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CREBBP Q92793 1/20 0.34
TDP2 O95551 1/20 0.33
NSD2 O96028 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PAX8 Q06710 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30109390 1.00 KDM4E (0.45) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL29396153 0.88 BRD4 (0.47) KDM4EALDH1A1HPGDMAOAMAOB
SCHEMBL1274983 0.88 BRD4 (0.47) KDM4EALDH1A1HPGDMAOAMAOB
SCHEMBL9579265 0.83 MAOA (0.59) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL15276007 0.83 KDM4E (0.40) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL23142108 0.83 KDM4E (0.61) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL18352941 0.83 BRD4 (0.41) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL30906133 0.83 MAOA (0.46) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL30067439 0.83 KDM4E (0.40) KDM4EALDH1A1HPGDGLAGAA
SCHEMBL1275336 0.83 MAOA (0.46) KDM4EALDH1A1HPGDGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441748-B2 Metal-ligand complexes DOW GLOBAL TECHNOLOGIES LLC (US) 2025-10-14 US disclosed
US-20240368001-A1 SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2024-11-07 US disclosed
US-11987506-B2 Salt recovery solution and processes of use thereof AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2024-05-21 US disclosed
US-20230257284-A1 SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2023-08-17 US disclosed
US-20230128137-A1 BENZO FIVE-MEMBERED CYCLIC COMPOUND MEDSHINE DISCOVERY INC. (CN) 2023-04-27 US disclosed
CN-111225875-B Salt recovery solution and method of using salt recovery solution 阿克福特斯技术有限公司 2023-04-11 CN disclosed
US-20230043356-A1 A SOLVENT DRYING COMPOSITION AND PROCESSES THEREFOR AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2023-02-09 US disclosed
CN-109715682-B Polymerization catalyst 尤尼威蒂恩技术有限责任公司 2022-09-30 CN disclosed
US-20220259231-A1 METAL-LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2022-08-18 US disclosed
EP-3519465-B1 POLYMERIZATION CATALYSTS UNIVATION TECH LLC (US) 2022-06-29 EP disclosed
US-5708018-A 2-aminoindans as selective dopamine D3 ligands PHARMACIA & UPJOHN COMPANY (US) 1998-01-13 US disclosed
EP-0712387-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS PHARMACIA & UPJOHN COMPANY (US) 1996-05-22 EP disclosed
EP-0693506-A2 Process for the preparation of amorphous polymers of propylene SPHERILENE S.p.A. (IT) 1996-01-24 EP disclosed
WO-1995004713-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS THE UPJOHN COMPANY (US) 1995-02-16 WO disclosed
US-5110989-A Pre- and postemergence; plant growth regulators ICI AUSTRALIA LIMITED (AU) 1992-05-05 US disclosed
US-4952722-A CYCLOHEX-2-EN-1-ONE DERIVATIVES; HERBICIDES ICI AUSTRALIA LIMITED (AU) 1990-08-28 US disclosed
EP-0086588-B1 CYCLOHEXANEDIONE DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PREPARING THEM ICI AUSTRALIA LIMITED (AU) 1987-07-01 EP disclosed
EP-0086588-A2 Cyclohexanedione derivatives, their use as herbicides, herbicidal compositions containing them, and methods of preparing them ICI AUSTRALIA LIMITED (AU) 1983-08-24 EP disclosed
US-4076726-A Amidino-hydrazone derivatives AKZONA INCORPORATED (US) 1978-02-28 US disclosed
US-4028380-A Hydrazino-imidazole derivatives AKZONA INCORPORATED (US) 1977-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259231-A1 METAL-LIGAND COMPLEXES ARL1, CRKL, SAAL1 KDM4E 3747/4885ALDH1A1 4147/4885HPGD 4737/4885
US-20230043356-A1 A SOLVENT DRYING COMPOSITION AND PROCESSES THEREFOR AQP1, AQP4, NOTUM KDM4E 4279/4885ALDH1A1 3984/4885HPGD 904/4885
US-20230128137-A1 BENZO FIVE-MEMBERED CYCLIC COMPOUND BCL2, BAX, BCL2L1 KDM4E 1702/4885ALDH1A1 3365/4885HPGD 2484/4885
US-12441748-B2 Metal-ligand complexes ARL1, CRKL, SAAL1 KDM4E 3747/4885ALDH1A1 4147/4885HPGD 4737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.