SCHEMBL8064474

SCHEMBL8064474

CC(C)(C)OC(=O)N1CC1Oc1ccc(Cl)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 2/20 0.41
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RBP4 P02753 3/20 0.41
KDM4E B2RXH2 2/20 0.40
CNR1 P21554 1/20 0.40
USP30 Q70CQ3 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PDE4B Q07343 1/20 0.38
GRM5 P41594 1/20 0.38
OPRK1 P41145 1/20 0.38
SUV39H2 Q9H5I1 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2299437 0.82 RBP4 (0.54) ALDH1A1MEN1KMT2ARBP4CNR1
SCHEMBL16759524 0.78 PDE4B (0.55) MEN1KMT2APDE4B
SCHEMBL1900868 0.74 SUV39H2 (0.48) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL19833905 0.74 RBP4 (0.61) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL1900872 0.74 SUV39H2 (0.48) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL1904867 0.74 SUV39H2 (0.48) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL30302137 0.73 ALDH1A1 (0.46) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL28961568 0.71 ALDH1A1 (0.59) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL24791799 0.71 MRGPRX4 (0.46) ALDH1A1MAPTKMT2ATSHRHTT
SCHEMBL12003024 0.70 NR1H2 (0.47) RBP4USP30PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853612-B1 ALPHA-HYDRAZINO ACID DERIVATIVES AND METHOD FOR MAKING SAME CENTRE NAT RECH SCIENT (FR) 2000-06-14 EP disclosed
US-5962722-A α-hydrazino acid derivatives and method for making same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1999-10-05 US disclosed
EP-0853612-A1 ALPHA-HYDRAZINO ACID DERIVATIVES AND METHOD FOR MAKING SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1998-07-22 EP disclosed
WO-1997009303-A1 ALPHA-HYDRAZINO ACID DERIVATIVES AND METHOD FOR MAKING SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1997-03-13 WO disclosed