Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FABP2 | P12104 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072952 | 1.00 | APP (0.40) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8079616 | 0.90 | MEN1 (0.42) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8064698 | 0.90 | MEN1 (0.42) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8075216 | 0.85 | ACMSD (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8074144 | 0.85 | ACMSD (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8065580 | 0.85 | AKR1C3 (0.45) | APPAKR1C3AKR1C2 | |
| SCHEMBL8080386 | 0.85 | AKR1C3 (0.49) | APPAKR1C3AKR1C2CTSAPTGS2 | |
| SCHEMBL8064468 | 0.85 | CTSA (0.36) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8078295 | 0.84 | SLC1A3 (0.39) | MMESLC1A3SLC1A2SLC1A1AKR1C3 | |
| SCHEMBL8073803 | 0.84 | SLC1A3 (0.39) | MMESLC1A3SLC1A2SLC1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |