Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.38 |
| ▸ | FEN1 | P39748 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064698 | 0.88 | MEN1 (0.42) | AKR1C3AKR1C2APP | |
| SCHEMBL8079616 | 0.88 | MEN1 (0.42) | AKR1C3AKR1C2APP | |
| SCHEMBL8074686 | 0.87 | PSEN1 (0.42) | AKR1C3AKR1C2PPARDPPARAFFAR1 | |
| SCHEMBL8064602 | 0.85 | APP (0.40) | AKR1C3AKR1C2APP | |
| SCHEMBL8072952 | 0.85 | APP (0.40) | AKR1C3AKR1C2APP | |
| SCHEMBL8078804 | 0.85 | SLC1A3 (0.46) | AKR1C3AKR1C2 | |
| SCHEMBL8075216 | 0.84 | ACMSD (0.40) | AKR1C3AKR1C2PPARGPPARAFFAR1 | |
| SCHEMBL8074144 | 0.84 | ACMSD (0.40) | AKR1C3AKR1C2PPARGPPARAFFAR1 | |
| SCHEMBL8080386 | 0.83 | AKR1C3 (0.49) | AKR1C3AKR1C2APP | |
| SCHEMBL8080154 | 0.81 | PPARG (0.41) | AKR1C3AKR1C2PPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | claimed |
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |