Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 4/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | DCLRE1B | Q9H816 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078295 | 1.00 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1MMEAKR1C3 | |
| SCHEMBL8075538 | 0.89 | DCLRE1B (0.39) | SLC1A3SLC1A2SLC1A1MMEDCLRE1B | |
| SCHEMBL8064541 | 0.89 | DCLRE1B (0.39) | SLC1A3SLC1A2SLC1A1MMEDCLRE1B | |
| SCHEMBL8075742 | 0.88 | DCLRE1B (0.40) | SLC1A3SLC1A2SLC1A1MMEDCLRE1B | |
| SCHEMBL8075087 | 0.86 | DCLRE1B (0.51) | MMEPTGER2DCLRE1BESR2PTGS2 | |
| SCHEMBL8073879 | 0.86 | DCLRE1B (0.51) | MMEPTGER2DCLRE1BESR2PTGS2 | |
| SCHEMBL8078431 | 0.85 | TTR (0.38) | SLC1A3SLC1A2SLC1A1AKR1C3AKR1C2 | |
| SCHEMBL8079616 | 0.84 | MEN1 (0.42) | MMEAKR1C3AKR1C2ACECPA1 | |
| SCHEMBL8075216 | 0.84 | ACMSD (0.40) | AKR1C3AKR1C2PTGS2 | |
| SCHEMBL8074144 | 0.84 | ACMSD (0.40) | AKR1C3AKR1C2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |