Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064678 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ACA2CA9 | |
| SCHEMBL8064681 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ACA2CA9 | |
| SCHEMBL8065752 | 0.92 | CA2 (0.37) | ALDH1A1MEN1KMT2ACA2CA9 | |
| SCHEMBL8065746 | 0.92 | CA2 (0.37) | ALDH1A1MEN1KMT2ACA2CA9 | |
| SCHEMBL8065750 | 0.92 | CA2 (0.37) | ALDH1A1MEN1KMT2ACA2CA9 | |
| SCHEMBL3243147 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACA2CA9 | |
| SCHEMBL3243149 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACA2CA9 | |
| SCHEMBL3243145 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACA2CA9 | |
| SCHEMBL5471045 | 0.85 | STAT3 (0.43) | ALDH1A1KMT2ACA2CA9STAT3 | |
| SCHEMBL5471050 | 0.85 | STAT3 (0.43) | ALDH1A1KMT2ACA2CA9STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093345-A | PYRIMIDINE COMPOUNDS, ELECTROOPTICS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-07-25 | — | — | US | disclosed |
| US-5454976-A | Optical active mixture comprising a fluoro-alkyl phenyl pyrimidine compounds; high contrast ratio, fast response time; optical switches, printer shutter arrays | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-10-03 | — | — | US | disclosed |