Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065752 | 1.00 | CA2 (0.37) | CA2CA9CA12STAT3ALDH1A1 | |
| SCHEMBL8065750 | 1.00 | CA2 (0.37) | CA2CA9CA12STAT3ALDH1A1 | |
| SCHEMBL8064678 | 0.92 | ALDH1A1 (0.39) | CA2CA9CA12STAT3ALDH1A1 | |
| SCHEMBL8064681 | 0.92 | ALDH1A1 (0.39) | CA2CA9CA12STAT3ALDH1A1 | |
| SCHEMBL8064683 | 0.92 | ALDH1A1 (0.39) | CA2CA9CA12STAT3ALDH1A1 | |
| SCHEMBL1061474 | 0.86 | CA2 (0.44) | CA2CA9CA12STAT3ALDH1A1 | |
| SCHEMBL9691197 | 0.86 | CA2 (0.44) | CA2CA9CA12STAT3ALDH1A1 | |
| SCHEMBL9691202 | 0.86 | CA2 (0.44) | CA2CA9CA12STAT3ALDH1A1 | |
| SCHEMBL9344197 | 0.85 | PLA2G2C (0.43) | CA2CA9CA12STAT3ALDH1A1 | |
| SCHEMBL9344192 | 0.85 | PLA2G2C (0.43) | CA2CA9CA12STAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093345-A | PYRIMIDINE COMPOUNDS, ELECTROOPTICS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-07-25 | — | — | US | disclosed |