Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064901 | 0.87 | TSHR (0.42) | BRD4CREBBPCES2CES1SLC6A2 | |
| SCHEMBL230519 | 0.79 | CES2 (0.49) | BRD4CES2CES1 | |
| SCHEMBL227352 | 0.79 | CES2 (0.55) | BRD4CES2CES1SLC6A2SLC6A4 | |
| SCHEMBL28788047 | 0.78 | BRD4 (0.49) | BRD4CREBBPCES2CES1OPRL1 | |
| SCHEMBL230487 | 0.77 | IDO1 (0.52) | BRD4CES2CES1SLC6A2SLC6A4 | |
| SCHEMBL8074148 | 0.77 | KMT2A (0.42) | KMT2ACES2CES1LPLLIPG | |
| SCHEMBL8077592 | 0.76 | CES2 (0.44) | KMT2ABRD4CREBBPCES2CES1 | |
| SCHEMBL6349980 | 0.75 | CES2 (0.45) | BRD4CES2CES1OPRL1SLC6A2 | |
| SCHEMBL5169427 | 0.74 | TAAR1 (0.57) | LPLLIPGSLC6A4 | |
| SCHEMBL13849445 | 0.74 | ESR1 (0.52) | OPRM1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |