Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064702 | 0.87 | KMT2A (0.40) | CES2CES1BRD4CREBBPSLC6A2 | |
| SCHEMBL8064208 | 0.82 | LMNA (0.53) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL230519 | 0.82 | CES2 (0.49) | CES2CES1BRD4HDAC4HDAC7 | |
| SCHEMBL8077592 | 0.82 | CES2 (0.44) | L3MBTL1CES2CES1BRD4CREBBP | |
| SCHEMBL227352 | 0.82 | CES2 (0.55) | CES2CES1BRD4SLC6A2SLC6A4 | |
| SCHEMBL28788047 | 0.81 | BRD4 (0.49) | CES2CES1BRD4CREBBPSLC6A2 | |
| SCHEMBL1632280 | 0.80 | TSHR (0.42) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL230487 | 0.80 | IDO1 (0.52) | CES2CES1BRD4SLC6A2SLC6A4 | |
| SCHEMBL6899388 | 0.80 | TP53 (0.54) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL6349980 | 0.77 | CES2 (0.45) | CES2CES1BRD4SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |