Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058003 | 0.95 | TSHR (0.51) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8057965 | 0.95 | TSHR (0.53) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8059997 | 0.93 | TSHR (0.47) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8059968 | 0.89 | TSHR (0.47) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3757194 | 0.88 | TSHR (0.45) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9778782 | 0.87 | TSHR (0.57) | TSHRPDE4AMEN1KMT2AMAPT | |
| SCHEMBL30669513 | 0.84 | TSHR (0.67) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8057984 | 0.84 | TSHR (0.67) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9778679 | 0.82 | HIF1A (0.49) | TSHRFDPSHIF1AEPAS1TP53 | |
| SCHEMBL9778850 | 0.82 | TSHR (0.57) | TSHRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004623-A1 | Aryl thioacetals useful as stabilizers in polymeric materials | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |