Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757194 | 0.94 | TSHR (0.45) | TSHRPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL8057965 | 0.93 | TSHR (0.53) | TSHRPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL8064807 | 0.93 | TSHR (0.53) | TSHRPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL8058003 | 0.88 | TSHR (0.51) | TSHRPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL9778817 | 0.86 | TSHR (0.50) | TSHRPDE4AMAOAMAOBKMT2A | |
| SCHEMBL8059968 | 0.82 | TSHR (0.47) | TSHRPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL12883744 | 0.81 | MAOA (0.55) | TSHRMAOAMAOBKMT2AMAPT | |
| SCHEMBL9778782 | 0.79 | TSHR (0.57) | TSHRPDE4AKMT2AMAPTMEN1 | |
| SCHEMBL9778850 | 0.79 | TSHR (0.57) | TSHRPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL9778629 | 0.79 | SIGMAR1 (0.41) | TSHRPPARGMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004623-A1 | Aryl thioacetals useful as stabilizers in polymeric materials | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |