Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058003 | 0.95 | TSHR (0.51) | TSHRPDE4ATHRATHRBMPO | |
| SCHEMBL8064807 | 0.89 | TSHR (0.53) | TSHRPDE4AMPOPDE4BPDE4C | |
| SCHEMBL3757194 | 0.88 | TSHR (0.45) | TSHRPDE4ATHRBPDE4BPDE4C | |
| SCHEMBL8057965 | 0.84 | TSHR (0.53) | TSHRPDE4AMPOPDE4BPDE4C | |
| SCHEMBL8059997 | 0.82 | TSHR (0.47) | TSHRPDE4AMPOPDE4BPDE4C | |
| SCHEMBL9778828 | 0.81 | TSHR (0.61) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9778782 | 0.79 | TSHR (0.57) | TSHRPDE4A | |
| SCHEMBL9778888 | 0.76 | APP (0.55) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8057984 | 0.75 | TSHR (0.67) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8975125 | 0.75 | THRA (0.53) | THRATHRBSMPD1PRSS1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004623-A1 | Aryl thioacetals useful as stabilizers in polymeric materials | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |