Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 5/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.49 |
| ▸ | GRM6 | O15303 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317301 | 0.85 | KIF11 (0.50) | — | |
| SCHEMBL1913648 | 0.85 | KIF11 (0.50) | — | |
| SCHEMBL8075228 | 0.78 | KIF11 (0.58) | — | |
| SCHEMBL8074690 | 0.77 | KIF11 (0.63) | — | |
| SCHEMBL6053554 | 0.76 | GRIK1 (0.48) | GRM8GRM4GRM6KMT2AMEN1 | |
| SCHEMBL6053553 | 0.76 | GRIK1 (0.48) | GRM8GRM4GRM6KMT2AMEN1 | |
| SCHEMBL7608097 | 0.75 | KDM4E (0.51) | MAPTNPSR1 | |
| SCHEMBL7607397 | 0.75 | KDM4E (0.51) | MAPTNPSR1 | |
| SCHEMBL8072634 | 0.75 | KIF11 (0.44) | — | |
| SCHEMBL5695662 | 0.73 | ACE (0.55) | GRM8GRM4GRM6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |