Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275122 | 1.00 | MAPT (0.40) | MAPTHPGDSLC6A2SLC6A4MT-CO2 | |
| SCHEMBL7837228 | 1.00 | MAPT (0.40) | MAPTHPGDSLC6A2SLC6A4MT-CO2 | |
| SCHEMBL16817775 | 0.94 | MAPT (0.41) | MAPTHPGDSLC6A2SLC6A4MEN1 | |
| SCHEMBL16817776 | 0.86 | MAPT (0.38) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL27836074 | 0.81 | ALDH1A1 (0.37) | HPGDSLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL8070409 | 0.74 | SIGMAR1 (0.43) | MEN1KMT2ALMNAPRCPTSHR | |
| Biphenyl SCHEMBL8160263 | 0.74 | ALDH1A1 (0.50) | SLC6A2SLC6A4MEN1KMT2AALDH1A1 | |
| Biphenyl SCHEMBL9507944 | 0.74 | ALDH1A1 (0.50) | SLC6A2SLC6A4MEN1KMT2AALDH1A1 | |
| SCHEMBL5534036 | 0.74 | HRH2 (0.41) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL7700085 | 0.74 | CHRNB4 (0.41) | MAPTMEN1KMT2AALDH1A1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025177-A | ENANTIOSELECTIVE SYNTHESIS OF CHIRAL ALPHA-HYDROXYCARBOXYLATE BY REACTING A PROCHIRAL ALPHA-KETOCARBOXYLIC ACID WITH A SINGLE ENANTIOMER OF AN N-SUBSTITUTED VICINAL AMINOALCOHOL OF SPECIFIC CYCLOHYDROCARBONS TO FORM ALPHA-HYDROXYCARBOXYLATE | SEPRACOR INC. (US) | 2000-02-15 | — | — | US | disclosed |