Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065025 | 1.00 | MMP8 (0.50) | MMP8NPY1RNPY2RELANEHPRT1 | |
| SCHEMBL4443858 | 0.86 | MMP9 (0.49) | MMP8MMP9MMP14L3MBTL1 | |
| SCHEMBL4443855 | 0.86 | MMP9 (0.49) | MMP8MMP9MMP14L3MBTL1 | |
| SCHEMBL4550562 | 0.85 | MMP9 (0.44) | MMP8MMP9MMP14POLBALDH1A1 | |
| SCHEMBL4550561 | 0.85 | MMP9 (0.44) | MMP8MMP9MMP14POLBALDH1A1 | |
| SCHEMBL2853134 | 0.84 | ITGA4 (0.53) | MMP9POLBALDH1A1ATM | |
| SCHEMBL2853138 | 0.84 | ITGA4 (0.53) | MMP9POLBALDH1A1ATM | |
| SCHEMBL28454174 | 0.83 | MMP8 (0.52) | MMP8NPY1RNPY2RELANEHPRT1 | |
| SCHEMBL15242293 | 0.83 | MMP8 (0.57) | MMP8NPY1RNPY2RELANEHPRT1 | |
| SCHEMBL7021895 | 0.81 | MMP8 (0.56) | MMP8ELANEHPRT1TP53TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006390-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |