Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806506 | 0.76 | SRD5A1 (0.49) | NR1H2NR1H3SRD5A1LMNATDP1 | |
| SCHEMBL15978294 | 0.76 | SRD5A1 (0.49) | NR1H2NR1H3SRD5A1LMNATDP1 | |
| SCHEMBL15978303 | 0.76 | SRD5A1 (0.46) | NR1H2NR1H3SRD5A1LMNATDP1 | |
| SCHEMBL806508 | 0.76 | SRD5A1 (0.46) | NR1H2NR1H3SRD5A1LMNATDP1 | |
| SCHEMBL15978295 | 0.76 | SRD5A1 (0.46) | NR1H2NR1H3SRD5A1LMNATDP1 | |
| SCHEMBL806727 | 0.76 | SRD5A1 (0.46) | NR1H2NR1H3SRD5A1LMNATDP1 | |
| SCHEMBL14455390 | 0.74 | NR1H2 (0.40) | NR1H2NR1H3SRD5A1LMNATDP1 | |
| SCHEMBL3091593 | 0.74 | LMNA (0.50) | NR1H2NR1H3SRD5A1LMNATDP1 | |
| SCHEMBL14456322 | 0.74 | LMNA (0.50) | NR1H2NR1H3SRD5A1LMNATDP1 | |
| SCHEMBL14695169 | 0.74 | LMNA (0.50) | NR1H2NR1H3SRD5A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629268-B2 | Cyclisation process of forming a multiple ring compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-01-14 | — | — | US | disclosed |
| US-20130046090-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-02-21 | — | — | US | disclosed |
| US-8227645-B2 | Cyclisation process of forming a multiple ring compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-07-24 | — | — | US | disclosed |
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-09-09 | — | — | US | disclosed |
| WO-2007097719-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | DHPS, GGPS1, COASY | NR1H2 524/4885NR1H3 643/4885SRD5A1 88/4885 |
| US-20130046090-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | COASY, AKR1C4, AKR1C2 | NR1H2 974/4885NR1H3 1112/4885SRD5A1 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.