SCHEMBL8065202

SCHEMBL8065202

C/C(c1ccccc1)=[Zr](\C1=CC=CC1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PNMT P11086 1/20 0.34
SRD5A2 P31213 1/20 0.33
HTR2B P41595 2/20 0.32
HTR7 P34969 1/20 0.32
CYP1A2 P05177 1/20 0.31
ADRA2A P08913 1/20 0.31
MAOA P21397 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1081333 0.89 NPC1 (0.39) NPC1RAB9APNMTSRD5A2HTR2B
Hydrochloric Acid SCHEMBL6908139 0.88 NPC1 (0.39) NPC1RAB9APNMTSRD5A2HTR2B
SCHEMBL4469957 0.87 NPC1 (0.45) NPC1RAB9APNMTSRD5A2HTR2B
Hydrochloric Acid SCHEMBL7634665 0.86 NPC1 (0.44) NPC1RAB9APNMTSRD5A2HTR2B
Hydrochloric Acid SCHEMBL6302943 0.86 NPC1 (0.44) NPC1RAB9APNMTSRD5A2HTR2B
Butane SCHEMBL7921892 0.83 NPC1 (0.41) NPC1RAB9APNMTHTR2BHTR7
SCHEMBL7040232 0.82 RAB9A (0.39) NPC1RAB9APNMTHTR2BHTR7
SCHEMBL16239749 0.81 NPC1 (0.37) NPC1RAB9APNMTHTR2BHTR7
Hydrochloric Acid SCHEMBL18280790 0.80 NPC1 (0.34) NPC1RAB9APNMTHTR2BHTR7
Hydrochloric Acid SCHEMBL673941 0.80 NPC1 (0.37) NPC1RAB9APNMTHTR2BHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0572990-B2 Method for preparing ethylene copolymer MITSUI TOATSU CHEMICALS (JP) 2000-08-16 EP claimed