Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469957 | 0.95 | NPC1 (0.45) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL7634665 | 0.94 | NPC1 (0.44) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL6302943 | 0.94 | NPC1 (0.44) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL7040232 | 0.90 | RAB9A (0.39) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL2807931 | 0.86 | NPC1 (0.37) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL8065202 | 0.83 | NPC1 (0.41) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL1081333 | 0.81 | NPC1 (0.39) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL16239749 | 0.81 | NPC1 (0.37) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL6433465 | 0.81 | NPC1 (0.37) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL6908139 | 0.81 | NPC1 (0.39) | NPC1RAB9APNMTHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946610-B1 | HIGH ACTIVITY METALLOCENE POLYMERIZATION PROCESS | EXXONMOBIL CHEM PATENTS INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6180736-B1 | USING SUPPORT AND A COMPLEX FORMED BY ACTIVATING A GROUP 3, 4, 5, OR 6 METALLOCENE COMPRISING UNSUBSTITUTED (TETRAHYDRO) INDENYL LIGAND AND UNSUBSTITUTED CYCLOPENTADIENYL LIGAND; ETHYLENE POLYMERS WITH NARROW MOLECULAR WEIGHT DISTRIBUTION | EXXON CHEMICAL PATENTS INC | 2001-01-30 | — | — | US | disclosed |
| EP-0946610-A1 | HIGH ACTIVITY METALLOCENE POLYMERIZATION PROCESS | EXXON CHEMICAL PATENTS INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028350-A1 | HIGH ACTIVITY METALLOCENE POLYMERIZATION PROCESS | EXXON CHEMICAL PATENTS INC. (US) | 1998-07-02 | — | — | WO | disclosed |