Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 15/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065463 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTADRA1ASCN9ABRD4 | |
| SCHEMBL11752886 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTADRA1ASCN9ABRD4 | |
| SCHEMBL19414342 | 0.76 | SCN9A (0.46) | SCN9ABRD4 | |
| SCHEMBL7093262 | 0.75 | MAPT (0.59) | ALDH1A1MAPTADRA1AKMT2A | |
| SCHEMBL11661462 | 0.74 | MAPT (0.57) | ALDH1A1MAPTADRA1AKMT2A | |
| SCHEMBL11661464 | 0.73 | POLB (0.55) | ALDH1A1MAPTADRA1ASCN9ABRD4 | |
| SCHEMBL11651032 | 0.73 | POLB (0.55) | ALDH1A1MAPTADRA1ASCN9ABRD4 | |
| SCHEMBL3477694 | 0.71 | BRD4 (0.52) | ALDH1A1SCN9ABRD4KMT2A | |
| SCHEMBL21783504 | 0.70 | SCN1A (0.53) | SCN9A | |
| Hydrochloric Acid SCHEMBL21955515 | 0.69 | SCN1A (0.52) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057359-A | NEW ESTERS OF BACCATIN-III, 10-DEACETYLBACCATIN-III AND 14-OH-10-DEACETYLBACCATIN-III USED FOR THE TREATMENT OF ECZEMA, PSORIASIS AND METABOLIC DISORDERS | MARIGEN S.A. (CH) | 2000-05-02 | — | — | US | disclosed |
| US-4133879-A | Process for producing stable solutions of a sulphonamide and a potentiator | AKTIESELSKABET ROSCO (DK) | 1979-01-09 | — | — | US | disclosed |
| US-4011332-A | RODENTICIDE | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1977-03-08 | — | — | US | disclosed |