Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16083225 | 0.85 | ALDH1A1 (0.65) | MEN1KMT2ANPSR1CYP3A4CYP2D6 | |
| SCHEMBL29401096 | 0.78 | MEN1 (0.62) | MEN1KMT2ANPSR1CYP3A4CYP2D6 | |
| SCHEMBL806585 | 0.76 | POLB (0.69) | MEN1KMT2ANPSR1CYP3A4CYP2D6 | |
| SCHEMBL16083226 | 0.75 | HTT (0.60) | MEN1KMT2ANPSR1CYP3A4CYP2D6 | |
| SCHEMBL806582 | 0.73 | GAA (0.66) | MEN1KMT2ANPSR1CYP3A4CYP2D6 | |
| SCHEMBL24445724 | 0.69 | MAPT (0.66) | MEN1KMT2ANPSR1CYP3A4CYP2D6 | |
| SCHEMBL31222507 | 0.69 | MAPT (0.66) | MEN1KMT2ANPSR1CYP3A4CYP2D6 | |
| SCHEMBL11888649 | 0.68 | GAA (0.64) | MEN1KMT2ANPSR1GAAPOLB | |
| SCHEMBL16557452 | 0.68 | LMNA (0.64) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30776642 | 0.67 | PKM (0.56) | MEN1KMT2ACYP3A4GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | MEN1 3791/4885KMT2A 1652/4885NPSR1 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.