Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236223 | 0.84 | ALDH1A1 (0.54) | KDM4EALDH1A1HSD17B10MAPTPKM | |
| Hydrochloric Acid SCHEMBL27401794 | 0.82 | ALDH1A1 (0.52) | KDM4EALDH1A1HSD17B10MAPTPKM | |
| SCHEMBL146130 | 0.82 | PTPN1 (0.63) | ALDH1A1HSD17B10MAPTPTPN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6744118 | 0.81 | PTPN1 (0.61) | ALDH1A1HSD17B10MAPTPTPN1SMN1; SMN2 | |
| SCHEMBL151790 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10MAPTPKM | |
| Trifluoroacetic Acid SCHEMBL27502379 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10MAPTPKM | |
| Formic Acid SCHEMBL28074373 | 0.76 | PTPN1 (0.55) | ALDH1A1MAPTPTPN1SMN1; SMN2ERCC5 | |
| SCHEMBL29999843 | 0.76 | CES2 (0.55) | ALDH1A1HSD17B10MAPTPTPN1SMN1; SMN2 | |
| SCHEMBL28504801 | 0.74 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10MAPTPKM | |
| SCHEMBL2199125 | 0.74 | MAPK1 (0.52) | KDM4EALDH1A1HSD17B10MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015028-A2 | METHODS TO IMPROVE IMMUNOGENICITY OF ANTIGENS AND SPECIFICITY OF ANTIBODIES | SEREX, INC. (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999013907-A2 | METHODS TO IMPROVE IMMUNOGENICITY OF ANTIGENS AND SPECIFICITY OF ANTIBODIES | SEREX, INC. (US) | 1999-03-25 | — | — | WO | disclosed |