Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066264 | 0.84 | MAPK1 (0.47) | ALDH1A1KMT2AHPGDTSHRPOLB | |
| SCHEMBL8472912 | 0.81 | HPGD (0.51) | ALDH1A1CYP2C9CYP2C19KMT2AHPGD | |
| SCHEMBL8067867 | 0.81 | POLB (0.49) | ALDH1A1CYP1A2CYP2C19KMT2AHPGD | |
| SCHEMBL8471904 | 0.79 | POLB (0.48) | ALDH1A1CYP1A2CYP2C19KMT2AHPGD | |
| SCHEMBL8475470 | 0.79 | HPGD (0.59) | ALDH1A1CYP2C9CYP2C19HPGDTSHR | |
| SCHEMBL8472155 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8474666 | 0.79 | HPGD (0.63) | ALDH1A1CYP2C9CYP2C19HPGDTSHR | |
| SCHEMBL22819344 | 0.79 | HPGD (0.65) | ALDH1A1HSD17B10HPGDTSHRPOLB | |
| SCHEMBL8066284 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDTSHRAPOBEC3AAPOBEC3G | |
| SCHEMBL8476172 | 0.78 | HPGD (0.66) | ALDH1A1CYP2C9CYP2C19HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994396-A | Furansulfonic acid derivatives and pharmaceutical compositions containing the same | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |