Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065479 | 0.84 | SMN1; SMN2 (0.48) | RIPK1LMNACHRNB2CHRNA4CLK1 | |
| SCHEMBL14276916 | 0.76 | SMN1; SMN2 (0.51) | RIPK1CHRNB2CHRNA4SMN1; SMN2KCNA5 | |
| SCHEMBL12277668 | 0.76 | RIPK1 (0.59) | RIPK1LMNACHRNB2CHRNA4CLK1 | |
| SCHEMBL8057291 | 0.73 | RIPK1 (0.64) | RIPK1LMNACHRNB2CHRNA4CLK1 | |
| SCHEMBL5890987 | 0.73 | LMNA (0.69) | RIPK1LMNACHRNB2CHRNA4CLK1 | |
| SCHEMBL12265796 | 0.73 | RIPK1 (0.76) | RIPK1LMNACHRNB2CHRNA4CLK1 | |
| SCHEMBL8470996 | 0.72 | RIPK1 (0.62) | RIPK1LMNACHRNB2CHRNA4CLK1 | |
| SCHEMBL14012798 | 0.72 | CHRNB2 (0.49) | RIPK1LMNACHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL14376115 | 0.72 | CHRNB2 (0.57) | RIPK1CHRNB2CHRNA4SMN1; SMN2KCNA5 | |
| SCHEMBL7663468 | 0.72 | RIPK1 (0.70) | RIPK1LMNACHRNB2CHRNA4CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124297-A | COMBATTING INSECTS OR MITES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | disclosed |
| EP-0302389-A2 | Alpha-unsaturated amines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |