Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 8/20 | 0.54 |
| ▸ | TRPC6 | Q9Y210 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IGF2BP1 | Q9NZI8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806654 | 0.84 | TRPC3 (0.75) | TRPC3TRPC6NPC1RAB9ANPSR1 | |
| SCHEMBL806599 | 0.73 | TRPC3 (0.58) | TRPC3TRPC6NPC1RAB9AALDH1A1 | |
| SCHEMBL10087862 | 0.73 | TRPC3 (0.60) | TRPC3TRPC6NPC1RAB9AALDH1A1 | |
| SCHEMBL806632 | 0.72 | TRPC3 (0.63) | TRPC3TRPC6GRM5TSHRMAPT | |
| SCHEMBL23771822 | 0.70 | TRPC3 (1.00) | TRPC3TRPC6NPC1RAB9AALDH1A1 | |
| SCHEMBL807014 | 0.69 | TRPC3 (0.73) | TRPC3TRPC6NPC1RAB9AALDH1A1 | |
| SCHEMBL26459144 | 0.69 | TRPC3 (0.72) | TRPC3TRPC6GRM5ALDH1A1TSHR | |
| SCHEMBL790188 | 0.69 | TRPC3 (0.72) | TRPC3TRPC6GRM5ALDH1A1TSHR | |
| SCHEMBL10087866 | 0.68 | TRPC3 (0.48) | TRPC3TRPC6NPC1RAB9AGRM5 | |
| SCHEMBL23771825 | 0.67 | TRPC3 (1.00) | TRPC3TRPC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037351-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |