Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 11/20 | 0.58 |
| ▸ | TRPC6 | Q9Y210 | 11/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087862 | 0.96 | TRPC3 (0.60) | TRPC3TRPC6HPGDSMN1; SMN2TSHR | |
| SCHEMBL806597 | 0.82 | TRPC3 (0.49) | TRPC3TRPC6SMN1; SMN2NPC1RAB9A | |
| SCHEMBL789220 | 0.77 | MAPT (0.53) | TRPC3TRPC6HPGDSMN1; SMN2TSHR | |
| SCHEMBL12503735 | 0.74 | TRPC3 (0.48) | TRPC3TRPC6HPGDSMN1; SMN2NPC1 | |
| SCHEMBL807014 | 0.74 | TRPC3 (0.73) | TRPC3TRPC6HPGDSMN1; SMN2NPC1 | |
| SCHEMBL806653 | 0.73 | TRPC3 (0.54) | TRPC3TRPC6TSHRNPC1RAB9A | |
| SCHEMBL807011 | 0.73 | TRPC3 (0.58) | TRPC3TRPC6HPGDSMN1; SMN2TSHR | |
| SCHEMBL806645 | 0.73 | TRPC3 (0.58) | TRPC3TRPC6HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10087863 | 0.73 | TRPC3 (0.58) | TRPC3TRPC6HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10087865 | 0.73 | TRPC3 (0.58) | TRPC3TRPC6HPGDSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037351-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |