Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 10/20 | 0.73 |
| ▸ | TRPC6 | Q9Y210 | 10/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807009 | 0.89 | TRPC3 (0.69) | TRPC3TRPC6ALDH1A1NPC1HPGD | |
| SCHEMBL23771823 | 0.84 | TRPC3 (1.00) | TRPC3TRPC6ALDH1A1NPC1HPGD | |
| SCHEMBL807013 | 0.81 | TRPC3 (1.00) | TRPC3TRPC6ALDH1A1NPC1HPGD | |
| SCHEMBL10080528 | 0.77 | RAB9A (0.58) | TRPC3TRPC6ALDH1A1NPC1HPGD | |
| SCHEMBL10080531 | 0.77 | TRPC3 (0.58) | TRPC3TRPC6ALDH1A1NPC1HPGD | |
| SCHEMBL10080530 | 0.77 | TRPC3 (0.63) | TRPC3TRPC6ALDH1A1NPC1HPGD | |
| SCHEMBL10080527 | 0.76 | TRPC3 (0.66) | TRPC3TRPC6ALDH1A1NPC1HPGD | |
| SCHEMBL10087862 | 0.76 | TRPC3 (0.60) | TRPC3TRPC6ALDH1A1NPC1HPGD | |
| SCHEMBL806599 | 0.74 | TRPC3 (0.58) | TRPC3TRPC6ALDH1A1NPC1HPGD | |
| SCHEMBL807012 | 0.73 | TRPC3 (0.62) | TRPC3TRPC6ALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037349-A2 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |