Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.50 |
| ▸ | ITGAV | P06756 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076280 | 0.85 | ITGB3 (0.64) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8070526 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL3379647 | 0.80 | CTSS (0.48) | ITGB3ITGA2B | |
| SCHEMBL3611054 | 0.80 | CTSS (0.48) | ITGB3ITGA2B | |
| SCHEMBL3379645 | 0.80 | CTSS (0.48) | ITGB3ITGA2B | |
| SCHEMBL15107465 | 0.80 | CTSS (0.48) | ITGB3ITGA2B | |
| SCHEMBL8071657 | 0.80 | ITGB3 (0.74) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7279022 | 0.79 | MAPK1 (0.52) | ITGB3ITGA2B | |
| SCHEMBL31738164 | 0.77 | HRH2 (0.49) | — | |
| SCHEMBL20439377 | 0.77 | CTSS (0.49) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |