Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.64 |
| ▸ | ITGAV | P06756 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071657 | 0.91 | ITGB3 (0.74) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8072985 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8076479 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8066595 | 0.85 | ITGB3 (0.50) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL15593763 | 0.83 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL16815979 | 0.83 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL8076407 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL3498974 | 0.83 | YAP1 (0.53) | ITGB3ITGA2B | |
| SCHEMBL3498976 | 0.83 | YAP1 (0.53) | ITGB3ITGA2B | |
| SCHEMBL5892285 | 0.82 | ITGB3 (0.60) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |