Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317490 | 0.85 | LMNA (0.44) | ALDH1A1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL3291904 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL1478701 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL10558853 | 0.84 | TSHR (0.47) | ALDH1A1CYP1A2CYP2D6CYP2C19TSHR | |
| SCHEMBL9899863 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL9859808 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNAKMT2ATSHRGPR35 | |
| SCHEMBL6121980 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAKMT2ATSHRGPR35 | |
| SCHEMBL2889129 | 0.79 | ALDH1A1 (0.68) | ALDH1A1CYP1A2LMNAKMT2ATSHR | |
| SCHEMBL7644871 | 0.79 | TSHR (0.62) | ALDH1A1CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL8064653 | 0.79 | PDGFRB (0.48) | ALDH1A1CYP1A2CYP2D6CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1016405-A2 | Arylating medicaments | Radopath Pharmaceuticals International Limited (GB) | 2000-07-05 | — | — | EP | claimed |
| CN-1124012-A | Arylating medicaments | RADOPATH LTD (GB) | 1996-06-05 | — | — | CN | claimed |
| EP-0700287-A1 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1996-03-13 | — | — | EP | claimed |
| WO-1994027584-A2 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1994-12-08 | — | — | WO | claimed |
| EP-1016405-A2 | Arylating medicaments | Radopath Pharmaceuticals International Limited (GB) | 2000-07-05 | — | — | EP | disclosed |
| EP-0700287-A1 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027584-A2 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |
| US-4169153-A | PROPHYLAXIS, ANTIHISTAMINES | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4091011-A | PROPHYLACTIC ANTIANAPHYLACTICS, ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1978-05-23 | — | — | US | disclosed |