Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068959 | 0.95 | EPHX1 (0.32) | EPHX1 | |
| Hydrochloric Acid SCHEMBL8072210 | 0.90 | MTNR1A (0.32) | EPHX1MTNR1AMTNR1BSMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8073534 | 0.88 | SMN1; SMN2 (0.36) | EPHX1MTNR1AMTNR1BSMN1; SMN2HPGD | |
| SCHEMBL8057784 | 0.85 | MTNR1A (0.31) | EPHX1MTNR1AMTNR1BSMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8073383 | 0.85 | EPHX1 (0.35) | EPHX1L3MBTL1 | |
| SCHEMBL8069038 | 0.83 | SMN1; SMN2 (0.35) | EPHX1MTNR1AMTNR1BSMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL8069069 | 0.80 | MTNR1A (0.34) | EPHX1MTNR1AMTNR1BSMN1; SMN2HPGD | |
| SCHEMBL8057641 | 0.80 | EPHX1 (0.33) | EPHX1 | |
| Hydrochloric Acid SCHEMBL8071406 | 0.79 | CYP1A2 (0.35) | EPHX1MTNR1AMTNR1BSMN1; SMN2HPGD | |
| SCHEMBL8068961 | 0.79 | IDH2 (0.32) | EPHX1MTNR1AMTNR1BSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127496-A | POLYMERIZING OLEFINICALLY UNSATURATED COMPOUNDS IN PRESENCE OF METALLOCENE CATALYST SYSTEM CONTAINING A COMPOUND CAPABLE OF FORMING METALLOCENIUM IONS | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-6077965-A | Metal complexes with an adamantane-like structure | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-20 | — | — | US | disclosed |