Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.68 |
| ▸ | CA12 | O43570 | 4/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.68 |
| ▸ | CA7 | P43166 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 6/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238491 | 0.83 | SYK (0.61) | CA1CA12CA14CA7SYK | |
| SCHEMBL964611 | 0.82 | CA1 (0.57) | CA1CA12CA14CA7CA2 | |
| SCHEMBL6337412 | 0.81 | CA12 (1.00) | CA1CA12CA14CA7CA2 | |
| SCHEMBL29206826 | 0.81 | CA1 (0.58) | CA1CA12CA14CA7CA2 | |
| SCHEMBL8488663 | 0.81 | ALDH1A1 (0.51) | CA1CA12CA14CA7CA2 | |
| SCHEMBL10072965 | 0.80 | SYK (0.52) | CA1CA12CA14CA7SYK | |
| SCHEMBL8244755 | 0.79 | CA12 (0.75) | CA1CA12CA14CA7CA2 | |
| SCHEMBL966252 | 0.78 | CA12 (0.74) | CA1CA12CA14CA7CA2 | |
| SCHEMBL25391654 | 0.78 | SYK (0.56) | SYKMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8180866 | 0.78 | SYK (0.56) | SYKMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159994-A | Histamine H3 receptor ligands | JAMES BLACK FOUNDATION (GB) | 2000-12-12 | — | — | US | disclosed |
| WO-1999005141-A1 | HISTAMINE H3 RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-02-04 | — | — | WO | disclosed |