Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815755 | 0.84 | RECQL (0.40) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL5515200 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL7823532 | 0.80 | MAPT (0.42) | ALDH1A1LMNAMAPTKDM4EKMT2A | |
| SCHEMBL8067005 | 0.80 | PDK1 (0.38) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL7822888 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL8909083 | 0.79 | SRC (0.52) | SRCALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL7868341 | 0.78 | MAPT (0.40) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7871688 | 0.78 | MEN1 (0.42) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL7827925 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL8068471 | 0.76 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |