Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 11/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816147 | 0.91 | PTGDR2 (0.42) | KMT2AALDH1A1HPGDAKR1C3AKR1C2 | |
| SCHEMBL8067988 | 0.90 | MKNK2 (0.43) | KMT2AALDH1A1HPGDAKR1C3AKR1C2 | |
| SCHEMBL7827515 | 0.89 | KMT2A (0.42) | KMT2AALDH1A1HPGDAKR1C3MEN1 | |
| SCHEMBL8068001 | 0.88 | ALDH1A1 (0.43) | KMT2AALDH1A1HPGDAKR1C3MEN1 | |
| SCHEMBL7826821 | 0.87 | UCHL1 (0.40) | KMT2AALDH1A1HPGDAKR1C3MEN1 | |
| SCHEMBL7827030 | 0.86 | UCHL1 (0.42) | KMT2AALDH1A1HPGDAKR1C3MEN1 | |
| SCHEMBL7827496 | 0.86 | MAPT (0.39) | KMT2AALDH1A1HPGDMEN1HSD17B10 | |
| SCHEMBL5515660 | 0.86 | UCHL1 (0.41) | KMT2AALDH1A1HPGDMEN1HSD17B10 | |
| SCHEMBL7816227 | 0.85 | UCHL1 (0.42) | ALDH1A1HPGDAKR1C3HSD17B10UCHL1 | |
| SCHEMBL7827679 | 0.84 | UCHL1 (0.40) | KMT2AALDH1A1HPGDHSD17B10UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |