SCHEMBL8067321

SCHEMBL8067321

CC(C)(C)c1ccc(OS(=O)(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
MAPT P10636 1/20 0.65
RECQL P46063 1/20 0.65
HSD11B1 P28845 1/20 0.59
HSD17B3 P37058 1/20 0.59
ENPP1 P22413 5/20 0.56
ENPP3 O14638 4/20 0.56
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
ENPP2 Q13822 1/20 0.54
UQCRB P14927 2/20 0.54
LMNA P02545 1/20 0.53
TYR P14679 1/20 0.53
KDM4E B2RXH2 1/20 0.52
KDM4A O75164 1/20 0.52
ELANE P08246 1/20 0.47
APEX1 P27695 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5150156 1.00 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AMAPTRECQL
SCHEMBL9310139 0.86 ALDH1A1 (0.64) ALDH1A1MEN1KMT2AMAPTRECQL
SCHEMBL872834 0.86 MEN1 (0.56) ALDH1A1MEN1KMT2AMAPTRECQL
SCHEMBL2990067 0.85 MEN1 (0.62) ALDH1A1MEN1KMT2AMAPTRECQL
Hydrogen Sulfide SCHEMBL15618664 0.83 MEN1 (0.61) ALDH1A1MEN1KMT2AMAPTRECQL
Iodide SCHEMBL29092642 0.83 MEN1 (0.61) ALDH1A1MEN1KMT2AMAPTRECQL
SCHEMBL8393963 0.83 HSD11B1 (0.62) ALDH1A1MEN1KMT2AMAPTRECQL
SCHEMBL2986520 0.83 TDP1 (0.61) ALDH1A1MEN1KMT2AMAPTRECQL
Hydrogen Sulfide SCHEMBL15619066 0.81 TDP1 (0.59) ALDH1A1MEN1KMT2AMAPTRECQL
SCHEMBL8794464 0.81 MEN1 (0.54) ALDH1A1MEN1KMT2AMAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2617710-B9 NOVEL PHENOLSULFONIC ACID ARYL ESTER DERIVATIVE, AND HEAT-SENSITIVE RECORDING MATERIAL USING SAME MITSUBISHI CHEM CORP (JP) 2016-07-13 EP disclosed
EP-2774916-B1 PHENOLSULFONIC ACID ARYL ESTER, DEVELOPING AGENT, AND HEAT-SENSITIVE RECORDING MATERIAL JUJO PAPER CO LTD (JP) 2016-05-25 EP disclosed
EP-2617710-B1 NOVEL PHENOLSULFONIC ACID ARYL ESTER DERIVATIVE, AND HEAT-SENSITIVE RECORDING MATERIAL USING SAME MITSUBISHI CHEM CORP (JP) 2015-11-18 EP disclosed
US-9073376-B2 Phenolsulfonic acid aryl ester, developing agent, and heat-sensitive recording material NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2015-07-07 US disclosed
US-8975212-B2 Phenolsulfonic acid aryl ester derivative, and heat-sensitive recording material using same MITSUBISHI CHEMICAL CORPORATION (JP) 2015-03-10 US disclosed
US-20140315713-A1 PHENOLSULFONIC ACID ARYL ESTER, DEVELOPING AGENT, AND HEAT-SENSITIVE RECORDING MATERIAL NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-10-23 US disclosed
EP-2774916-A1 PHENOLSULFONIC ACID ARYL ESTER, DEVELOPING AGENT, AND HEAT-SENSITIVE RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2014-09-10 EP disclosed
US-20130237414-A1 NOVEL PHENOLSULFONIC ACID ARYL ESTER DERIVATIVE, AND HEAT-SENSITIVE RECORDING MATERIAL USING SAME NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-09-12 US disclosed
EP-2617710-A1 NOVEL PHENOLSULFONIC ACID ARYL ESTER DERIVATIVE, AND HEAT-SENSITIVE RECORDING MATERIAL USING SAME API Corporation (JP) 2013-07-24 EP disclosed
EP-0219302-B2 Recording materials FUJI PHOTO FILM CO LTD (JP) 2000-06-28 EP disclosed
US-4800193-A ANILINE, INDOLE AND PHTHALEIN DYES; COLORFASTNESS; AROMATIC SOLVENT-SOLUBLE FUJI PHOTO FILM CO., LTD. (JP) 1989-01-24 US disclosed
US-4797385-A LEUCO DYES, STARCH PARTICLES FUJI PHOTO FILM CO., LTD. (JP) 1989-01-10 US disclosed
US-4792542-A CONTAINING AN AROMATIC SULFIDE FUJI PHOTO FILM CO., LTD. (JP) 1988-12-20 US disclosed
US-4771034-A LEUCO DYE, SALICYCLIC ACID DERIVATIVE AS ELECTRON ACCEPTOR FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
EP-0262810-A2 Sheet recording material containing dye-forming components Fuji Photo Film Co., Ltd. (JP) 1988-04-06 EP disclosed
US-4728633-A HEAT AND PRESSURE SENSITIVE ELEMENTS FUJI PHOTO FILM CO., LTD. (JP) 1988-03-01 US disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
EP-0222343-A2 Recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-05-20 EP disclosed
EP-0219302-A2 Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1987-04-22 EP disclosed
US-4583104-A Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1986-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140315713-A1 PHENOLSULFONIC ACID ARYL ESTER, DEVELOPING AGENT, AND HEAT-SENSITIVE RECORDING MATERIAL ARSA, AHNAK, HSPA4L ALDH1A1 656/4885MEN1 4513/4885KMT2A 3164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.