Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807059 | 0.90 | PIK3C3 (0.46) | PIK3C3PI4KAPIK3CGGAKKDM4E | |
| SCHEMBL10274836 | 0.90 | KCNH2 (0.48) | PIK3C3PIK3CGKDM4EALDH1A1HPGD | |
| SCHEMBL807061 | 0.89 | ATR (0.43) | KITPIK3C3PI4KAPIK3CGMAPT | |
| SCHEMBL807455 | 0.83 | PI4KA (0.55) | PI4KAPIK3CGPIK3CDPIK3R1 | |
| SCHEMBL807470 | 0.82 | PIK3CG (0.55) | PI4KAPIK3CGPIK3CDPIK3R1 | |
| SCHEMBL807137 | 0.81 | PIK3CG (0.75) | PI4KAPIK3CGPIK3CDPIK3R1 | |
| SCHEMBL807223 | 0.79 | IRAK4 (0.46) | KITPI4KAPIK3CGLRRK2IRAK4 | |
| SCHEMBL10274687 | 0.79 | PI4KA (0.64) | KITPI4KAPIK3CGLRRK2IRAK4 | |
| SCHEMBL806789 | 0.77 | PIK3CD (0.50) | KITPIK3CGLRRK2IRAK4NTRK1 | |
| SCHEMBL10274839 | 0.76 | MAPT (0.56) | PI4KAPIK3CGIRAK4PIK3CDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |