Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 9/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10274836 | 0.91 | KCNH2 (0.48) | PIK3C3HPGDMAPTCASP1AURKA | |
| SCHEMBL807061 | 0.90 | ATR (0.43) | PIK3C3MAPTCASP1AURKATTK | |
| SCHEMBL806763 | 0.90 | KIT (0.49) | PIK3C3HPGDMAPTGAKRAB9A | |
| SCHEMBL807240 | 0.80 | PIK3CG (0.67) | PI4KAPIK3CG | |
| SCHEMBL10274839 | 0.77 | MAPT (0.56) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL789820 | 0.77 | ALDH1A1 (0.43) | PIK3C3HPGDTDP1RAB9AKDM4E | |
| SCHEMBL807455 | 0.74 | PI4KA (0.55) | PI4KAPIK3CG | |
| SCHEMBL807470 | 0.73 | PIK3CG (0.55) | PI4KAPIK3CG | |
| SCHEMBL806791 | 0.73 | PI4KA (0.43) | PIK3C3HPGDRAB9AKDM4EALDH1A1 | |
| SCHEMBL789777 | 0.73 | PIK3CG (0.66) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |