SCHEMBL8067754

SCHEMBL8067754

OB(O)c1ccc(-c2ccccc2)c(B(O)O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.54
CA1 P00915 3/20 0.54
MGLL Q99685 2/20 0.54
ENPP2 Q13822 5/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
BACE1 P56817 1/20 0.41
ESR2 Q92731 1/20 0.41
ALOX5 P09917 1/20 0.41
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
TRPV1 Q8NER1 1/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL971733 0.83 CA1 (0.58) CA2CA1MGLLENPP2CA4
SCHEMBL257768 0.82 ESR2 (0.58) CA2CA1MGLLENPP2CA4
SCHEMBL12551788 0.82 MGLL (0.50) CA2CA1MGLLBACE1ESR2
SCHEMBL18649277 0.80 CA1 (0.54) CA2CA1MGLLENPP2CA4
SCHEMBL25217035 0.80 ESR2 (0.46) CA2CA1MGLLBACE1ESR2
SCHEMBL30421069 0.80 ESR2 (0.46) CA2CA1MGLLBACE1ESR2
SCHEMBL3110322 0.78 KMT2A (0.44) MGLLBACE1ESR2ALOX5ALDH1A1
SCHEMBL3655307 0.78 PTGDR2 (0.41) CA2CA1MGLLBACE1ESR2
SCHEMBL28972658 0.78 ESR2 (0.40) CA2CA1MGLLBACE1ESR2
SCHEMBL625451 0.78 CA1 (0.52) CA2CA1MGLLENPP2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115487866-B Covalent organic framework material coupling nano metal catalyst and preparation method thereof 浙江大学 2024-05-14 CN claimed
CN-117024974-A Ablation-resistant and impact-resistant resin matrix and preparation method and application thereof 中国科学院化学研究所 2023-11-10 CN claimed
CN-114773756-B Thermo-mechanical stable supermolecular elastomer material and preparation method thereof 四川大学 2023-08-22 CN claimed
CN-110523354-B Preparation method of microreactor containing immobilized catalyst 浙江大学 2021-01-19 CN claimed
CN-110790251-A Preparation method of porous carbon material with high thermal oxygen stability and regular pore channel structure 中国科学技术大学 2020-02-14 CN claimed
CN-117024974-A Ablation-resistant and impact-resistant resin matrix and preparation method and application thereof 中国科学院化学研究所 2023-11-10 CN disclosed
CN-114773756-B Thermo-mechanical stable supermolecular elastomer material and preparation method thereof 四川大学 2023-08-22 CN disclosed
CN-116093283-A Phthalocyanine-based covalent organic framework coated nano silicon composite material and preparation method thereof 宜春江理锂电新能源产业研究院 2023-05-09 CN disclosed
CN-114638513-A Radioactive waste solidification treatment evaluation method and alternative nuclide feasibility evaluation method 中广核研究院有限公司 2022-06-17 CN disclosed
CN-112840021-A Compounds for stabilizing hydrolases in liquids 巴斯夫欧洲公司 2021-05-25 CN disclosed
CN-112805376-A Compounds for stabilizing hydrolases in liquids 巴斯夫欧洲公司 2021-05-14 CN disclosed
CN-112805377-A Compounds for stabilizing amylases in liquids 巴斯夫欧洲公司 2021-05-14 CN disclosed
CN-112409374-A Preparation method of rigid core direct-connected graphene-like benzophenanthrene discotic liquid crystal and mesomorphism 四川师范大学 2021-02-26 CN disclosed
CN-110523354-B Preparation method of microreactor containing immobilized catalyst 浙江大学 2021-01-19 CN disclosed
CN-110487735-B Gas sensor based on covalent organic framework material and preparation method thereof 浙江大学 2020-10-16 CN disclosed
CN-111417707-A Storage-stable enzyme preparations, their production and use 巴斯夫欧洲公司 2020-07-14 CN disclosed
CN-110790251-A Preparation method of porous carbon material with high thermal oxygen stability and regular pore channel structure 中国科学技术大学 2020-02-14 CN disclosed
EP-1009415-A4 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR UNIV NORTHWESTERN (US) 2000-10-25 EP disclosed
EP-1009415-A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR NORTHWESTERN UNIVERSITY (US) 2000-06-21 EP disclosed
WO-1998056392-A1 INHIBITORS OF β-LACTAMASES AND USES THEREFOR NORTHWESTERN UNIVERSITY (US) 1998-12-17 WO disclosed