SCHEMBL3655307

SCHEMBL3655307

OB(O)c1cc(Br)ccc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 3/20 0.41
BACE1 P56817 1/20 0.40
ESR2 Q92731 1/20 0.40
CYP19A1 P11511 1/20 0.40
ALOX5 P09917 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
MGLL Q99685 2/20 0.38
LMNA P02545 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PTPRC P08575 1/20 0.37
HTT P42858 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25320059 0.85 PTGDR2 (0.45) PTGDR2ALDH1A1MAPK1BACE1ESR2
SCHEMBL28450257 0.80 PTGDR2 (0.42) PTGDR2ALDH1A1MAPK1BACE1ESR2
SCHEMBL12551788 0.80 MGLL (0.50) ALDH1A1BACE1ESR2ALOX5MGLL
SCHEMBL30421069 0.78 ESR2 (0.46) PTGDR2ALDH1A1MAPK1BACE1ESR2
SCHEMBL8067754 0.78 CA2 (0.54) ALDH1A1BACE1ESR2ALOX5MGLL
SCHEMBL25217035 0.78 ESR2 (0.46) PTGDR2ALDH1A1MAPK1BACE1ESR2
SCHEMBL8420427 0.77 ALDH1A1 (0.43) ALDH1A1MAPK1BACE1ESR2ALOX5
SCHEMBL3110322 0.77 KMT2A (0.44) PTGDR2ALDH1A1MAPK1BACE1ESR2
SCHEMBL28972658 0.77 ESR2 (0.40) BACE1ESR2ALOX5AKR1C3AKR1C2
SCHEMBL8775538 0.76 SLC6A3 (0.46) ALDH1A1MAPK1MGLLLMNACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10134997-B2 Indenopyridine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-11-20 US disclosed
US-20150060808-A1 INDENOPYRIDINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2015-03-05 US disclosed
US-20110054229-A1 LUMINESCENT COMPOUNDS AND ELECTROLUMINESCENT DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2011-03-03 US disclosed
EP-2215185-A1 LUMINESCENT COMPOUNDS AND ELECTROLUMINESCENT DEVICE USING THE SAME Gracel Display Inc. (KR) 2010-08-11 EP disclosed
WO-2009066815-A1 LUMINESCENT COMPOUNDS AND ELECTROLUMINESCENT DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2009-05-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054229-A1 LUMINESCENT COMPOUNDS AND ELECTROLUMINESCENT DEVICE USING THE SAME OCIAD2, OCIAD1, ORMDL3 PTGDR2 3123/4885ALDH1A1 574/4885MAPK1 3026/4885
US-10134997-B2 Indenopyridine-based compound and organic light-emitting device including the same QDPR, CACNA1D, TPMT PTGDR2 213/4885ALDH1A1 127/4885MAPK1 2456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.