SCHEMBL3110322

SCHEMBL3110322

OB(O)c1cc(Cl)ccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HSD11B1 P28845 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
CYP1A2 P05177 1/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
BACE1 P56817 1/20 0.40
AURKA O14965 1/20 0.40
AURKB Q96GD4 1/20 0.40
ESR2 Q92731 1/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20164147 0.85 PTGDR2 (0.45) KMT2AMEN1RXFP1PTGDR2CYP1A2
SCHEMBL12551788 0.80 MGLL (0.50) KMT2AMEN1ALDH1A1SMN1; SMN2NPC1
SCHEMBL25217035 0.78 ESR2 (0.46) KMT2AMEN1PTGDR2MAPK1ALDH1A1
SCHEMBL8067754 0.78 CA2 (0.54) ALDH1A1BACE1ESR2HPGDHSD17B10
SCHEMBL30421069 0.78 ESR2 (0.46) KMT2AMEN1PTGDR2MAPK1ALDH1A1
SCHEMBL3655307 0.77 PTGDR2 (0.41) PTGDR2MAPK1ALDH1A1BACE1ESR2
SCHEMBL28972658 0.77 ESR2 (0.40) KMT2AMEN1CYP1A2BACE1ESR2
SCHEMBL28545275 0.77 METAP2 (0.37) KMT2AMEN1RXFP1PTGDR2CYP1A2
SCHEMBL29664280 0.76 SLC6A4 (0.47) KMT2AMEN1CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL1742339 0.76 SLC6A4 (0.47) KMT2AMEN1CYP1A2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116332914-B Compound for organic electric element, organic electric element using the same, and electronic device using the same 德山新勒克斯有限公司 2025-04-15 CN disclosed
CN-111836872-B Compound for organic electric element, organic electric element using the same, and electronic device using the same 德山新勒克斯有限公司 2023-10-24 CN disclosed
CN-116507623-A Heterocyclic compound, organic light-emitting element comprising same, method for producing same, and composition for organic layer LT素材株式会社 2023-07-28 CN disclosed
CN-116332914-A Compound for organic electric element, organic electric element using the same, and electronic device using the same 德山新勒克斯有限公司 2023-06-27 CN disclosed
CN-116332916-A Compound for organic electric element, organic electric element using the same, and electronic device using the same 德山新勒克斯有限公司 2023-06-27 CN disclosed
US-11538996-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
EP-3679024-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-11-02 EP disclosed
CN-111836872-A Compound for organic electric element, organic electric element using the same, and electronic device thereof 德山新勒克斯有限公司 2020-10-27 CN disclosed
US-20200283386-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-09-10 US disclosed
EP-3419960-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-07-01 EP disclosed
US-9716232-B2 Material for organic light-emitting device, and organic light-emitting device using same LG CHEM, LTD. (KR) 2017-07-25 US disclosed
EP-2755253-B1 MATERIAL FOR ORGANIC LIGHT-EMITTING DEVICE, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2017-06-28 EP disclosed
CN-103797604-B Material for organic light emitting device and organic light emitting device using the same 株式会社LG化学 2017-02-15 CN disclosed
US-9553270-B2 Material for organic light-emitting device, and organic light-emitting device using same LG CHEM, LTD. (KR) 2017-01-24 US disclosed
CN-103797605-B Material for organic light emitting device and organic light emitting device using the same 株式会社LG化学 2016-12-21 CN disclosed
US-20140231774-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING DEVICE, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2014-08-21 US disclosed
US-20140183517-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING DEVICE, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2014-07-03 US disclosed
EP-2198867-A1 Pyrimidine-based compounds useful as GSK-3 inhibitors Vertex Pharmaceuticals, Inc. (US) 2010-06-23 EP disclosed
EP-1474147-B1 PYRIMIDINE-BASED COMPOUNDS USEFUL AS GSK-3 INHIBITORS VERTEX PHARMA (US) 2010-05-05 EP disclosed
US-20030199526-A1 Pyrimidine-based compounds useful as GSK-3 inhibitors VERTEX PHARMACEUTICALS, INCORPORATED 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199526-A1 Pyrimidine-based compounds useful as GSK-3 inhibitors GSK3B, GSK3A, GSKIP KMT2A 2096/4885MEN1 3790/4885RXFP1 4566/4885
US-11538996-B2 Materials for organic electroluminescent devices RIF1, INTS9, LEF1 KMT2A 3719/4885MEN1 138/4885RXFP1 3415/4885
US-20200283386-A1 MATERIALS FOR ELECTRONIC DEVICES EFNA1, GPX1, SOD1 KMT2A 2546/4885MEN1 408/4885RXFP1 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.