Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.44 |
| ▸ | CNR1 | P21554 | 6/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14317987 | 0.95 | PI4KB (0.42) | CNR2CNR1ADRA2ANPY5RMCHR1 | |
| SCHEMBL14305923 | 0.82 | SMN1; SMN2 (0.57) | GLASMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL9955406 | 0.80 | GLA (0.42) | GLASMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL9954020 | 0.80 | PIK3C3 (0.49) | SMN1; SMN2MEN1POLBKMT2APIK3C3 | |
| SCHEMBL10289140 | 0.79 | KMT2A (0.44) | GLASMN1; SMN2MEN1KMT2ASHMT2 | |
| SCHEMBL9953570 | 0.79 | LMNA (0.55) | SMN1; SMN2POLBKMT2A | |
| SCHEMBL10289139 | 0.78 | GAA (0.55) | GLASMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL9954303 | 0.78 | PLA2G1B (0.41) | GLASMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL9954686 | 0.78 | PIK3C3 (0.53) | SMN1; SMN2MEN1POLBKMT2APIK3C3 | |
| SCHEMBL14305926 | 0.78 | PIK3C3 (0.55) | SMN1; SMN2MEN1POLBKMT2APIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |