Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305923 | 0.81 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL9953391 | 0.81 | POLB (0.54) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9955026 | 0.81 | TSHR (0.55) | LMNAALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL743351 | 0.81 | POLB (0.55) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9954777 | 0.81 | PIK3CD (0.56) | KMT2AMAPT | |
| SCHEMBL9955406 | 0.79 | GLA (0.42) | SMN1; SMN2KMT2APOLB | |
| SCHEMBL14247664 | 0.79 | ALDH1A1 (0.53) | LMNACYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL806779 | 0.79 | CNR2 (0.44) | SMN1; SMN2KMT2APOLB | |
| SCHEMBL31113449 | 0.78 | ALDH1A1 (0.74) | LMNACYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL10289140 | 0.78 | KMT2A (0.44) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |