Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8058965 | 0.89 | MMP2 (0.51) | MAPTL3MBTL1MMP2MMP9ADAM10 | |
| Hydrochloric Acid SCHEMBL8069339 | 0.84 | HTT (0.50) | MMP2MMP9FOLH1HTTSIRT2 | |
| SCHEMBL7318212 | 0.84 | FOLH1 (0.58) | MMP2MMP9FOLH1HTTSIRT2 | |
| SCHEMBL7311020 | 0.84 | FOLH1 (0.58) | MMP2MMP9FOLH1HTTSIRT2 | |
| Hydrochloric Acid SCHEMBL8074447 | 0.82 | MMP2 (0.53) | MMP2MMP9ADAM10MMP14ADAM17 | |
| Hydrochloric Acid SCHEMBL8068240 | 0.81 | HTT (0.53) | MMP2MMP9FOLH1HTTSIRT2 | |
| Hydrochloric Acid SCHEMBL8070255 | 0.81 | TGM2 (0.50) | CTSSMMP2MMP9MMP14FOLH1 | |
| SCHEMBL8069618 | 0.80 | CTSS (0.42) | CTSSCTSKMAPTL3MBTL1FOLH1 | |
| SCHEMBL8068132 | 0.80 | CTSS (0.42) | CTSSCTSKMAPTL3MBTL1MMP2 | |
| SCHEMBL8120405 | 0.77 | HTT (0.56) | MMP2MMP9FOLH1HTTSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |