Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12245400 | 0.83 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL9747476 | 0.77 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL8070045 | 0.77 | CYP11B1 (0.61) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL394308 | 0.76 | CYP11B1 (0.83) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL12299569 | 0.75 | CYP11B1 (0.71) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL5478998 | 0.75 | CYP19A1 (0.73) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL15125651 | 0.74 | CYP11B1 (0.72) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL13153034 | 0.74 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL9853963 | 0.73 | CYP19A1 (0.80) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL24247782 | 0.73 | CYP19A1 (0.70) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36617-E | Anastrozole and salts as anticancer agent | ZENECA LIMITED (GB) | 2000-03-14 | — | — | US | disclosed |
| EP-0296749-B1 | (Substituted aralkyl) heterocyclic compounds | ZENECA LTD (GB) | 1994-10-26 | — | — | EP | disclosed |
| US-4935437-A | (Substituted aralkyl) heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-19 | — | — | US | disclosed |