Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070260 | 0.92 | FOLH1 (0.42) | FOLH1HTTMAPTL3MBTL1SLC1A3 | |
| SCHEMBL8068011 | 0.92 | MAPT (0.43) | FOLH1HTTMAPTL3MBTL1SLC1A3 | |
| SCHEMBL8068125 | 0.92 | FOLH1 (0.42) | FOLH1NPC1RAB9AHTTKMT2A | |
| SCHEMBL8114425 | 0.91 | ATM (0.46) | ATMFOLH1HTTMAPTL3MBTL1 | |
| SCHEMBL8069648 | 0.91 | FOLH1 (0.44) | FOLH1HTTSLC1A3SLC1A1CNR1 | |
| SCHEMBL8069819 | 0.91 | MMP2 (0.45) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL8071280 | 0.90 | ATM (0.40) | ATMFOLH1NPC1GAARAB9A | |
| SCHEMBL8070175 | 0.90 | FOLH1 (0.42) | FOLH1HTTSLC1A3SLC1A1CNR1 | |
| SCHEMBL8069625 | 0.90 | PSMB5 (0.44) | ATMFOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL8072950 | 0.89 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |