Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068125 | 0.90 | FOLH1 (0.42) | PSMB5FOLH1MTNR1AMTNR1BHTT | |
| SCHEMBL8068280 | 0.90 | ATM (0.45) | FOLH1ATMHTTCA1CA2 | |
| SCHEMBL8059164 | 0.89 | FOLH1 (0.42) | FOLH1HTTCA1CA2SLC1A3 | |
| SCHEMBL8068235 | 0.89 | MTNR1A (0.40) | MTNR1AMTNR1BPOLB | |
| SCHEMBL8114425 | 0.84 | ATM (0.46) | FOLH1ATMHTTCA1CA2 | |
| SCHEMBL8069648 | 0.84 | FOLH1 (0.44) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL8070260 | 0.84 | FOLH1 (0.42) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL8068011 | 0.84 | MAPT (0.43) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL8072950 | 0.83 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL8068008 | 0.82 | MTNR1A (0.37) | PSMB5FOLH1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |