Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056983 | 0.83 | HDAC6 (0.58) | PTGDR2HDAC1HDAC6FAAHHDAC10 | |
| SCHEMBL6484797 | 0.82 | HDAC1 (0.49) | PTGDR2ALDH1A1MAPTHDAC1HDAC6 | |
| SCHEMBL3085461 | 0.80 | PTGDR2 (0.81) | PTGDR2HDAC1HDAC6HDAC10HDAC8 | |
| SCHEMBL4185797 | 0.78 | HDAC1 (0.56) | PTGDR2HDAC1HDAC6 | |
| SCHEMBL8068712 | 0.77 | CCKBR (0.44) | PTGDR2CCKBRMAPTHDAC8 | |
| SCHEMBL8057235 | 0.76 | HDAC1 (0.52) | PTGDR2HDAC1HDAC6HDAC10 | |
| SCHEMBL7220006 | 0.75 | MAPT (0.54) | PTGDR2ALDH1A1MAPT | |
| SCHEMBL6421798 | 0.74 | HDAC1 (0.55) | PTGDR2HDAC1HDAC6 | |
| SCHEMBL6421094 | 0.74 | PTGDR2 (0.59) | PTGDR2HDAC1HDAC6 | |
| SCHEMBL8068660 | 0.73 | CCKBR (0.52) | ALDH1A1CCKBRRAB9AMAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057311-A | TREATING EATING DISORDERS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-02 | — | — | US | disclosed |
| WO-1997032860-A1 | BENZODIAZONINE DERIVATIVES BINDING TO CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |