SCHEMBL8068752

SCHEMBL8068752

C[S+]([O-])c1ccc(C(=O)Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
TSHR P16473 1/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CES2 O00748 2/20 0.30
CES1 P23141 2/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17907433 0.82 ALDH1A1 (0.48) ALDH1A1LMNA
SCHEMBL3644304 0.80 TSHR (0.55) ALDH1A1TSHRCA1CA2CES2
SCHEMBL31256698 0.80 MAPK1 (0.47) ALDH1A1LMNA
SCHEMBL3974617 0.78 PARP10 (0.47) ALDH1A1TSHRCA1CA2LMNA
SCHEMBL10830356 0.78 GSK3B (0.53) ALDH1A1CA1CA2
SCHEMBL8190024 0.77 CPT1B (0.50) CES2CES1
SCHEMBL10033092 0.76 ALDH1A1 (0.47) ALDH1A1TSHRCA1CA2CES2
SCHEMBL8779728 0.75
SCHEMBL68148 0.75 ALDH1A1 (0.59) ALDH1A1TSHRCA1CA2CES2
SCHEMBL20587670 0.75 ALDH1A1 (0.59) ALDH1A1TSHRCA1CA2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409623-A Ketoxime ester photoinitiator and application thereof, and photosensitive composition 武汉尚赛光电科技有限公司 2025-02-11 CN disclosed
US-6020379-A Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia CELL PATHWAYS, INC. (US) 2000-02-01 US disclosed
EP-0072346-B1 AMIDINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOUNDS CONTAINING THEM AND THEIR USE CIBA-GEIGY AG (CH) 1986-04-09 EP disclosed
US-4444768-A ICE CREAM CONE WRAPPER CIBA-GEIGY CORPORATION (US) 1984-04-24 US disclosed
EP-0072346-A2 Amidines, process for their preparation, pharmaceutical compounds containing them and their use CIBA-GEIGY AG (CH) 1983-02-16 EP disclosed
US-4057642-A ANTIINFLAMMATORY, RHEUMATOID ARTHRITIS MERCK & CO., INC. (US) 1977-11-08 US disclosed
US-4009164-A Novel 2-substituted-1,2,4-thiadiazole-[2,3-a]-benzimidazoles and process for their preparation SYNTEX (U.S.A.) INC. (US) 1977-02-22 US disclosed
US-3979404-A FUNGICIDES SYNTEX (U.S.A.) INC. (US) 1976-09-07 US disclosed
US-3976654-A FUNGICIDE SYNTEX (U.S.A.) INC. (US) 1976-08-24 US disclosed
US-3954852-A Indenylacetic acid compounds MERCK & CO., INC. (US) 1976-05-04 US disclosed
US-3946031-A FUNGICIDES SYNTEX INC. (US) 1976-03-23 US disclosed