SCHEMBL17907433

SCHEMBL17907433

C[S+]([O-])c1ccc(C(=O)c2ccc([S+](C)[O-])cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
LMNA P02545 2/20 0.48
SRD5A2 P31213 6/20 0.44
HPGD P15428 3/20 0.44
MAPT P10636 2/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
PKM P14618 1/20 0.44
HTT P42858 1/20 0.44
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8065192 0.92 ALDH1A1 (0.56) ALDH1A1LMNASRD5A2HPGDMAPT
SCHEMBL7592062 0.92 LMNA (0.60) ALDH1A1LMNASRD5A2HPGDMAPT
SCHEMBL31256698 0.84 MAPK1 (0.47) ALDH1A1LMNAHPGDMAPTNPC1
SCHEMBL3644304 0.84 TSHR (0.55) ALDH1A1SRD5A2HPGD
SCHEMBL8068752 0.82 ALDH1A1 (0.45) ALDH1A1LMNA
SCHEMBL3974617 0.82 PARP10 (0.47) ALDH1A1LMNAMAPT
SCHEMBL8190024 0.80 CPT1B (0.50) RAB9A
SCHEMBL8779728 0.79
SCHEMBL10226600 0.79 CES2 (0.60) LMNAHPGDMAPTRAB9A
SCHEMBL31185587 0.79 SMN1; SMN2 (0.50) ALDH1A1HPGDMAPTHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10982049-B2 Polyarylene sulfide resin and manufacturing method therefor, poly(arylene sulfonium salt) and manufacturing method therefor, and sulfoxide DIC CORPORATION (JP) 2021-04-20 US disclosed
EP-3042924-B1 POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE DAINIPPON INK & CHEMICALS (JP) 2020-04-29 EP disclosed
EP-3636632-A1 POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENESULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE DIC Corporation (JP) 2020-04-15 EP disclosed
US-10577464-B2 Polyarylene sulfide resin, method for producing same, poly(arylene sulfonium salt), and method for producing poly(arylene sulfonium salt) DIC CORPORATION (JP) 2020-03-03 US disclosed
US-20190300652-A1 POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE DAINIPPON INK & CHEMICALS (JP) 2019-10-03 US disclosed
US-10385168-B2 Polyarylene sulfide resin and manufacturing method therefor, poly(arylenesulfonium salt) and manufacturing method therefor, and sulfoxide DIC CORPORATION (JP) 2019-08-20 US disclosed
US-20180057635-A1 POLYARYLENE SULFIDE RESIN, METHOD FOR PRODUCING SAME, POLY(ARYLENE SULFONIUM SALT), AND METHOD FOR PRODUCING POLY(ARYLENE SULFONIUM SALT) DIC CORPORATION (JP) 2018-03-01 US disclosed
CN-105492498-B Polyarylene sulfide resin and method for producing same, poly (arylene sulfonium salt) and method for producing same, and sulfoxide DIC株式会社 2018-02-13 CN disclosed
CN-107428938-A Polyarylene sulfide resin and method for producing same, and poly (arylsulfonium salt) and method for producing same DIC株式会社 2017-12-01 CN disclosed
US-20170218126-A1 POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE DAINIPPON INK & CHEMICALS (JP) 2017-08-03 US disclosed
US-9657142-B2 Polyarylene sulfide resin and manufacturing method therefor, poly(arylene sulfonium salt) and manufacturing method therefor, and sulfoxide DIC CORPORATION (JP) 2017-05-23 US disclosed
US-20160200874-A1 POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE DIC CORPORATION (JP) 2016-07-14 US disclosed
EP-3042924-A1 POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE DIC Corporation (JP) 2016-07-13 EP disclosed
CN-105492498-A Polyarylene sulfide resin and method for producing same, poly (arylene sulfonium salt) and method for producing same, and sulfoxide DAINIPPON INK & CHEMICALS 2016-04-13 CN disclosed
CN-1305486-A Novel compounds derived from alpha-D-xylose, preparation method and therapeutic use FOURNIER IND & SANTE (FR) 2001-07-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190300652-A1 POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE GARS1, ASH2L, SULT1A1 ALDH1A1 231/4885LMNA 4748/4885SRD5A2 715/4885
US-20160200874-A1 POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE GARS1, ASH2L, SULT1A1 ALDH1A1 231/4885LMNA 4748/4885SRD5A2 715/4885
US-10982049-B2 Polyarylene sulfide resin and manufacturing method therefor, poly(arylene sulfonium salt) and manufacturing method therefor, and sulfoxide GARS1, ASH2L, SULT1A1 ALDH1A1 231/4885LMNA 4748/4885SRD5A2 715/4885
US-20170218126-A1 POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE GARS1, ASH2L, SULT1A1 ALDH1A1 231/4885LMNA 4748/4885SRD5A2 715/4885
US-10385168-B2 Polyarylene sulfide resin and manufacturing method therefor, poly(arylenesulfonium salt) and manufacturing method therefor, and sulfoxide GARS1, ASH2L, SULT1A1 ALDH1A1 209/4885LMNA 4730/4885SRD5A2 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.